But there is not much information available about the safety of long-term use.

There isn't enough information about the safety of long-term use.

Long-term use of the drug has been associated with some serious side effects.

There is still a need for studies that look at long-term use - over 10 years.

The safety of long-term use, more than 8 weeks, is not known.

But they added that there was not enough data on long-term use of the other drugs.

The safety of long-term use (beyond 3 months) is not known.

Recently completed studies show that these effects continue with long-term use.

This is another area in which long-term use has not been demonstrated.

Some evidence also suggests that long-term use up to 75 weeks may be safe.