The last word that the mysterious hand had written was filled with important significance.

It's people who play a dollar or two on a number with significance.

The trial was designed to have an 80% power, with significance set at the 5% level.

But they were to come back to me with significance later.

The battle over deregulation is an issue with great political significance.

And also the fact that the wedding is being loaded with significance.

Her eyes met mine with significance as she said: "She'll be safer out of here for the next hour or so."

However, the term was not defined with significance until the 20th century.

He does not trouble himself with the play's symbolism or significance.

No one paid much attention to his words then, but later they were recalled with significance.