It would be a once-in-a-lifetime chance to find out.
From another perspective, it is a once-in-a-lifetime chance to do and study whatever gets you going!
These are once-in-a-lifetime chances that won't happen for 99 percent of them again.
I always wanted to visit America and this is a once-in-a-lifetime chance.
It was literally a once-in-a-lifetime chance for both of us, and I'm terribly glad we went.
He says the whole thing in Nipponese except for "once-in-a-lifetime chance."
The first half of next year is a once-in-a-lifetime chance to explore these countries at a bargain price with much smaller crowds than usual.
We should be thinking of Wednesday as a once-in-a-lifetime chance.
The sale gave some buyers a once-in-a-lifetime chance to make a debut on a Broadway stage.
All the while he was thinking out loud, talking about missed opportunities and once-in-a-lifetime chances.