A study with low power is unlikely to lead to a large change in beliefs.

The term can refer to small or large changes of focus.

"We don't expect large changes in the 1995 data," she said.

We would not make such a large change without formal consultation.

There has been a large change in the way that the 32 songs will be selected.

It could lead to larger changes in the way political business is carried out here.

It seems all the large changes of my life take place at the year's failing.

It is also rooted in larger social changes, she added.

But there were very large changes of another kind here.

However, one large change was to occur very late in development.