This means that in spite of their differences, there is "an inner similarity and commonality" among things, which forms a single world.

And, in spite of their extreme differences, these brothers were actually very fond of each other.

In spite of all our obvious differences, Kwan thinks she and 1 are exactly alike.

In spite of our differences, I would not desert you in that manner.

They intuitively shared the risk, which was one thing that made them a good team in spite of their differences.

In spite of their many differences, they were enough alike to work well as partners.

In spite of their differences, however, many commonalities were brought to light by the research.

In spite of their differences, family members have a lot in common.

It brings them together in spite of their differences.

In spite of their differences, they remained firm political allies.