Moreover, variability does not seem confined to any particular region of the extracellular domain, but is spread uniformly across its length.

The large extracellular domains make up approximately 76-100% of the receptor.

It is thought that the well-conserved extracellular domains serve as receptors to control the activities of the channels.

It is an extracellular domain found in many receptors.

In structure, they share cadherin repeats, which are the extracellular Ca-binding domains.

The extracellular domain serves as the ligand-binding part of the molecule.

These proteins have extracellular domains that interact with each other on adjacent cells.

Most mutations affect the extracellular domain of the receptor, some also the cleavage site.

The neurotransmitters bind at the interface between subunits in the extracellular domain.

The extracellular domain is encoded by the central 11 exons.