"You," she examined her remaining grapes with care, "are a despicable person of weak moral fiber."

Although thought of as a despicable person, he is highly professional in accomplishing assigned tasks.

For a time, I thought her a despicable person.

"I thought I was a despicable person," she says.

Add to that, vanity and coquettishness and there's no question about it: she's a thoroughly despicable person.

Oh you are a despicable person; I want nothing to do with you.

The title really refers to the occupational hazard, in the movie business, of becoming a despicable person, fast.

Maybe he really was a despicable person and that was why the role had come so easy to him.

A pimp can also mean "a despicable person".

Rather, it refers to a mean, despicable, or vicious person, or any particularly difficult or frustrating situation.