It is still difficult to head a young company in a business where many of the best-known designers are men and a less-established company often loses clients to big-name firms.

One of Canada's best-known designers, he led a tenyear campaign for the professional accreditation of graphic designers in Ontario.

A handful of the best-known designers, like Giorgio Armani and Donna Karan, are pampered by store executives, but the rest are constantly vying for attention.

Traveling Italians A contingent of Italy's best-known designers and manufacturers has arrived for the opening today of Moda Italia.

Each season some of Ireland's best-known designers create collections for Tipperary Crystal.

The initial public offering by one of the nation's best-known designers already has fashion investors clamoring for shares.

The neighborhood has many trendy European-style bistros, fashion emporiums and boutiques that showcase Japan's best-known designers.

Anne Klein, who died in 1974, was one of America's best-known designers for day clothes - separates and suits - in the 1970's.

"The timing seemed right to bring back Manoeuvres once more," said Mr. Charron, one of Montreal's best-known graphic designers.

The years of relentless marketing paid off: at his peak, Wright was far and away the best-known designer in America.