From the 1920s through 1950s the city was a major center for country music.
The district is a major center for education and learning.
But what if going to a major medical center makes the difference between life and death?
It is the only major cultural center in the east of the city.
So instead, the company wants to make it part of a major cultural center on 125th Street.
This is a major shopping center for the people of old city.
The movie ran for more than 250 days in major centers.
It was also a major commercial center, and home industry production reached high levels.
It is also a major center of higher education in central Russia.
The district is the major center of sugar production in the country.