The loss of family stability can lead to depression in several ways.

The losses led to calls for the resignation of the national leadership.

The loss of accreditation led some students to make plans to transfer.

This loss led to the formation of the community's first volunteer fire department.

Further, destruction and loss of income led to significant financial losses.

The loss of Flight 44-2 also led to new airline safety rules.

The losses led to questions about the viability of the club.

The loss of many manufacturing jobs led to a decline in population and property values.

Her loss to Harris led to a major shift in the political orientation of the party.

The loss of this old farming practice led to the species's decline.