use-dependent

Use-dependent slowing of conduction was seen in all studies during drug infusion.

Use-dependent brain activity is a result of the neuronal usage that occurred during the previous waking hours.

This strong association between musician status and gray matter differences supports the notion that musicians' brains show use-dependent structural changes.

Philanthotoxin appeared to be a use-dependent antagonist consistent with a channel-blocking mode of action.

Suppression of the depolarization rate is use-dependent(7), and therefore inhibition increases with increased stimulation.

Amiodarone prolongation of the action potential is uniform over a wide range of heart rates so this drug does not have reverse use-dependent action.

The binding of ryanodine to RyRs is use-dependent, that is the channels have to be in the activated state.

Thus, these four Ca antagonists have a prominent use-dependent component in their actions, and one or two may also have a use-independent component.

Stellate stimulation significantly reduced use-dependent prolongation of the HV interval by an average of 60%.

(iv) Tonic block and use-dependent block with TP treatment, which was induced by increasing the frequency of stimulation, occurred.

These results may implicate that nicardipine blocks the postsynaptic acetylcholine receptor channel by enhancing receptor desensitization or by a use-dependent effect.

Canadian Project Leader of a multilateral research group involving three Canadian universities and three German universities investigating use-dependent plasticity in humans.

The action of CgNa is not use-dependent, as activation of the sodium channels by repetitive stimuli does not increase the effectiveness of CgNa.

Perampanel is a selective negative allosteric AMPA receptor antagonist of high-affinity and slow blocking kinetics, and is not use-dependent.

A use-dependent effect on conduction was assessed by measuring the change in the His to surface ventricular activation (HV) time at differing atrial paced rates during drug infusion.

The human brain and nervous system, it turns out, are built and sculpted, neuron by neuron, through the interaction of our particular genes and experiences, in what is called use-dependent development.

The block of BK cells is voltage-, concentration- and use-dependent, meaning the blockage changes with different stimulation voltages and frequencies, different concentrations and with the duration of application of tertiapin.

Abstract: Two forms of use-dependent synaptic plasticity, called long-term potentiation (LTP) and long-term depression (LTD), can be elicited in the visual cortex following different paradigms of electrophysiological stimulation.

Walsh's research career focuses on understanding how synapses in the basal ganglia, and in particular, corticostriatal synapses are modified by use or experience and how these use-dependent changes in synapses strength translate into behavior.

Since the fraction of inactive channels is increased by membrane depolarization as well as by repetitive firing, the binding to the inactive state by phenytoin sodium can produce voltage-dependent, use-dependent and time-dependent block of sodium-dependent action potentials.