ubiquitin conjugating enzyme , UBC (Abkürzung)

PFL0190w (E2) is 147 amino acid residues in length and contains an ubiquitin conjugating enzyme domain takes up almost its whole length.

In addition, we required an ubiquitin activating enzyme (E1) and an ubiquitin conjugating enzyme (UBC).

Ubiquitin conjugating enzyme E2D2 (UBE2D2) is a protein that targets abnormal or short-lived proteins for degradation by the 26S proteasome [ 28 ] .

The tail anchored membrane protein Ubc6 as well as Ubc1 and the Cue1 dependent membrane bound Ubc7 are the ubiquitin conjugating enzymes involved in ERAD.

The ubiquitin transfer reaction involves three enzymes: E1, which mediates the ATP-dependent activation of ubiquitin, and E2, or ubiquitin conjugating enzyme (UBC), which, together with an E3 ubiquitin ligase, transfers ubiquitin to the target protein.