thromboxane

People who take a baby aspirin a day for 10 days have no thromboxane at all left in their platelets.

The prototype for these drugs is aspirin, which inhibits the production of thromboxane.

Leucotrienes produce contraction of this tissue and thromboxane has no effect.

Thromboxane is named for its role in clot formation (thrombosis).

Effect of onion and ginger consumption on platelet thromboxane production in humans.

This could fit with the hypothesis concerning the prostacyclin/thromboxane imbalance.

Increased thromboxane A 2 production may also contribute to thrombogenesis in atherosclerotic vessels.

Thromboxane is a member of the family of lipids known as eicosanoids.

Thromboxane is thought to cause platelets in the blood to stick together, leading to blood clots.

Thromboxane A2 functions to activate more platelets, and this leads to a greater chance for blood clots to form.

For many years scientists have ascribed aspirin's exclusive heart benefits entirely to its dramatic effects on thromboxane and platelets.

Thromboxane A2 (TX2) has a positive feedback in platelet activation.

Because of its highly unstable nature, various thromboxane A 2 -generating systems have to be used in order to study its vasoactive properties.

Thromboxane A2 is also a known vasoconstrictor and is especially important during tissue injury and inflammation.

This prevents them from making a powerful substance, called a thromboxane, that stimulates them to aggregate and form a clot.

The combined effect of thromboxane, then, is to promote the formation of a clot that would clog a blood vessel.

Merck's scientists say that naproxen appears to help reduce heart attacks by stopping or slowing the production of a substance called thromboxane.

Thromboxane causes adherence of neutrophils and vasoconstriction.

Terbogrel is a thromboxane A2 receptor antagonist.

Although platelet thromboxane generation was elevated in diabetics without clinical evidence of vascular disease, the difference did not reach statistical significance.

The two major thromboxanes are thromboxane A2 and thromboxane B2.

Discussion Ibuprofen is a reversible, short-acting cyclooxygenase inhibitor, which particularly blocks the synthesis of thromboxane.

This causes the phosphorylation of a p38MAPkinase, resulting in the production of thromboxane A2.

Identification of an enzyme in platelet microsomes which generates thromboxane A2 from prostaglandin endoperoxides.

However, aggregating platelets also stimulate thromboxane A2 and serotonin which can induce contraction of the smooth muscle cells.