suberic acid

Suberic acid it was first produced by nitric acid oxidation of cork (Latin suber).

Suberic acid was used in the manufacture of alkyd resins and in the synthesis of polyamides (nylon variants).

Suberic acid, also octanedioic acid, is a dicarboxylic acid, with formula CHO.

In 1836, French chemist Jean-Baptiste Boussingault first synthesized cycloheptanone from the calcium salt of dibasic suberic acid.

Cycloheptanone is still produced by the cyclization and decarboxylation of suberic acid or suberic acid esters.

It is found that the cavity dimensions are optimal for inclusion of suberic acid but that with a longer acid sebacic acid or a shorter acid adipic acid the interaction is less favorable.

The following values seem to be aberrant in children with CASK gene defects: lactate, pyruvate, 2-ketoglutarate, adipic acid and suberic acid, which seems to backup the proposal that CASK affects mitochondrial function.