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It is also believed that this method causes a larger recruitment of nociceptor units resulting in a spatial summation.
If multiple synapses are simultaneously activated, dendritic spikes may be formed through spatial summation.
Spatial summation is a way of achieving an action potential in a neuron which involves input from multiple presynaptic cells.
This spatial summation results in a much larger barrage of signals to the dorsal horn and brainstem neurons.
Spatial summation involves the addition of multiple input signals resulting in a larger signal and possibly a dendritic spike.
Spatial summation: If a cell is receiving input at two synapses that are near each other, their postsynaptic potentials add together.
This ensured that the light stimulus fell only on rod cells connected to the same nerve fibre (this is called the area of spatial summation).
Furthermore, the regions exhibit mutual cancellation (antagonism) and produce stronger responses as the stimuli fill more space (spatial summation).
Furthermore, much like the subordinate processing cells, increasing illumination in a particular region elicited stronger responses (i.e. spatial summation).
Spatial summation is the algebraic summation of potentials from different areas of input, usually on the dendrites.
Spatial summation began to receive a lot of research attention when techniques were developed that allowed the simultaneous recording of multiple loci on a dendritic tree.
Hippocampal CA1 neurons have been shown to produce reliable dendritic spike propagation through spatial summation of multiple synaptic inputs.
Neurons which receive relatively few inputs cannot rely on spatial summation and therefore must rely on stronger synaptic inputs.
Indeed, through pressure stimulation experiments, it has been shown that spatial summation facilitates temporal summation of nociceptive inputs, specifically pressure pain.
Other more branched neurons, such as the pyramidal neurons, rely on spatial summation of multiple inputs to generate forward propagating dendritic spikes.
In a similar way, the postsynaptic neuron can sum together EPSPs from multiple synapses with other neurons in a process called spatial summation.
Their work showed that spatial summation of excitatory and inhibitory postsynaptic potentials caused attenuation of the excitatory response during the inhibitory response most of the time.
Regarding nociceptive stimulation, spatial summation is the ability to integrate painful input from large areas while temporal summation refers to the ability of integrating repetitive nociceptive stimuli.
Conduction velocity is average, spatial summation within the receptive field is linear (they have a null position usually), the receptive field has a centre-surround organization, and receptive fields are small.
Accordingly, the hypercomplex cell will respond, with spatial summation, to stimuli on the left side (within the activating region) insofar as it does not extend further into the right side (antagonistic region).
This is due to spatial summation of rods, so 100 rods could merge into many bipolars, in turn converging on ganglion cells, and the unit for resolution is very large, thus acuity being small.
Spatial summation means that the effects of impulses received at different places on the neuron add up, so that the neuron may fire when such impulses are received simultaneously, even if each impulse on its own would not be sufficient to cause firing.
Spatial summation is the combination of multiple sources of ion influx (multiple channels within a dendrite, or channels within multiple dendrites), where temporal summation is a gradual increase in overall charge due to repeated influxes in the same location.
This is called spatial summation and is complemented by temporal summation, wherein successive releases of transmitter from one synapse will cause progressive polarization change as long as the presynaptic changes occur faster than the decay rate of the membrane potential changes in the postsynaptic neuron.