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A finding of lasting pharmacological interest from these studies was the identification and partial isolation of the slow-reacting substance of anaphylaxis.
The cysteinyl leukotrienes make up the slow-reacting substance of anaphylaxis (SRS-A).
The Slow-reacting substance of anaphylaxis or SRS-A is a mixture of the leukotrienes LTC4, LTD4 and LTE4.