Researchers identified the maturation promoting factor that regulates cell division, and discovered the T-cell receptor which trigger responses of the immune system.
This recognition was done by a T-cell receptor on the surface of the T cell.
At this stage they must create a unique T-cell receptor through V(D)J recombination.
They looked at 100,000 genetic bases that make up the gene responsible for the body's production of the T-cell receptor, a critical part of the immune system.
They determined that one type of T-cell receptor predominated in the rally against proteins on the surface of myelin tissue.
The majority of cases, greater than 90%, contain a clonal rearrangement of the T-cell receptor.
The most accepted hypothesis is that dialogue between T-cell receptors and myelin antigens leads to an immune attack on the myelin-oligodendrocyte complex.
Immature thymocytes each make distinct T-cell receptors by a process of gene rearrangement.
Immature thymocytes undergo a process of selection, based on the specificity of their T-cell receptors.
It also supports signaling from T-cell receptors.
Wörterbuch für Biologie