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Holmes' tremor is a combination of rest, action, and postural tremors.
A person who has a postural tremor will shake while sitting or standing, but not while lying down.
A postural tremor may also accompany intention tremors.
Postural tremors.
Cerebellar damage can also produce a "wing-beating" type of tremor called rubral or Holmes' tremor - a combination of rest, action, and postural tremors.
Other types of tremor may also occur, including postural tremor of the outstretched arms, intentional tremor of the arms and rest tremor in the arms.
The neurotoxic effects of long term use (in particular repeated withdrawals) of toluene may cause postural tremors by upregulating GABA receptors within the cerebellar cortex.
In individuals with the condition, tremor tends to occur while voluntarily maintaining a fixed posture against gravity ("postural tremor") or while performing certain goal-directed movements ("kinetic intention tremor").
Progressive muscle wasting results in weakness of distal limb muscles (especially the peronei), gait ataxia, pes cavus, postural tremors and static tremor of the upper limbs, kyphoscoliosis, and foot deformity.
Cerebellar tremor may be accompanied by other manifestations of ataxia, including dysarthria (speech problems), nystagmus (rapid, involuntary rolling of the eyes), gait problems and postural tremor of the trunk and neck.
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