pooled plasma

This test is repeated with pooled plasma from normal patients.

The thrombin time compares the rate of clot formation to that of a sample of normal pooled plasma.

If a clotting inhibitor such as a lupus anticoagulant is present, the inhibitor will interact with the normal pooled plasma and the clotting time will remain abnormal.

The initial workup of a prolonged PTT is a mixing test whereby the patient's plasma is mixed with normal pooled plasma and the clotting is re-assessed.

For treatment, he received weekly transfusions of Factor VIII, a blood product created from pooled plasma of non-hemophiliacs, an increasingly common treatment for hemophiliacs at the time.

Both of these concentrates are prepared from pooled plasma, and the risk of virus transmission is negligible as there hasn't been an infection since 1985 when techniques were developed to kill off viruses including HIV.

Further investigation showed that the patients had contracted Hepatitis B from pooled plasma, which led to changes in transfusion practices and resulted in a significant reduction in illness and death among soldiers being treated.

Fractionation involves changing the conditions of the pooled plasma (e.g., the temperature or the acidity) so that proteins that are normally dissolved in the plasma fluid become insoluble, forming large clumps, called precipitate.

SD plasma is made from pooled plasma from thousands of donors that is specially treated to destroy certain viruses, including H.I.V. and hepatitis C, which may occasionally get into the blood supply despite current screening methods.

The initial response was to heat-treat (pasteurise) plasma-derived factor concentrate, followed by the development of monoclonal factor concentrates, which use a combination of heat treatment and affinity chromatography to inactivate any viral agents in the pooled plasma from which the factor concentrate is derived.

Noticing a high occurrence of severe hepatitis in wounded soldiers who received blood transfusions, Dr. Ginsberg determined that the pooled plasma the hospital was giving its patients was causing hepatitis B. For his efforts, the Army gave him its Legion of Merit Award in 1945.