pleomorphism

Nuclear pleomorphism is usually minimal and mitoses are infrequently seen.

There are usually small centrally placed nuclei without pleomorphism.

"That's more pleomorphism than you see with plague.

The concept of pleomorphism was quite controversial at the end of the 19th and the beginning of the 20th century.

However, a cambium layer, abnormal mitoses and nuclear pleomorphism is not seen.

Nuclear pleomorphism is usually easily to identify, with the nuclei containing prominent nucleoli.

It derives its name from the architectural pleomorphism (variable appearance) seen by light microscopy.

The virions of certain viruses are sometimes seen to express pleomorphism, in the sense that they can show variable appearances.

He caused more sensation, however, when he developed and published his concepts about the pleomorphism of microorganisms.

"But you do see the pleomorphism?"

Confocal microscopy revealed significant pleomorphism and polymegethism of endothelial cells.

His hypotheses about pleomorphism and cancer have now been disproved by science and have only some historical importance today.

Cellular (cytoplasmic) pleomorphism (atypia) - cells are of abnormal and different shapes.

These demonstrate various degrees of cytologic atypia, including hyperchromasia, pleomorphism, prominent nucleoli.

By microscopic examination, there are haphazardly arranged thick collage fibers, with a low cellularity and no pleomorphism.

Marked intragroup nuclear pleomorphism.

There is usually minimal pleomorphism but less commonly there can be anaplasia, mitotic activity, and necrosis.

Anaplastic cells display marked pleomorphism.

Pleomorphism may refer to:

Certain benign cell types may have pleomorphism, e.g. neuroendocrine cells, Arias-Stella reaction.

Immunodeficiency-associated Burkitt lymphoma may demonstrate more plasmacytic appearance or more pleomorphism, but these features are not specific.

Morphologic features suggesting malignancy (cellular pleomorphism, hyperchromatic nuclei, necrosis, high mitotic activity) can occasionally be seen.

Histopathology will reveal prominent intercellular bridges and nuclear changes such as pleomorphism, hyperchromatism and prominent nucleoli.

Depending on glandular architecture, cellular pleomorphism and mucosecretion, adenocarcinoma may present 3 degrees of differentiation: well, moderate and poorly differentiated.

Therefore, several histologic parameters, including degree of cellularity, cellular pleomorphism, mitotic activity, degree of necrosis, and invasive growth, are evaluated in the grading process.