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Molecular mimicry between Fc receptor and S peplomer protein of mouse hepatitis virus, bovine corona virus, and transmissible gastroenteritis virus.
The ribbon diagram shows the chain of the spike protein.
Each type of coronavirus has a distinct spike protein.
The spike protein has two sub-units called gp1 and gp2 which wrap around one another oddly, they reported in the journal Nature.
The researchers have a picture of the so-called spike protein, used by many viruses to get into the cells they infect.
This temporal control allows the spike proteins to be produced last, and therefore, delay recognition by the host immune system.
This spike protein shares similar deletions with group 2 coronaviruses in the C-terminus.
Glycosylation and oligomerization of the spike protein of Marburg virus.
Immunogenicity of porcine transmissible gastroenteritis virus spike protein expressed in plants.
The spike protein (VP4) is glycoslyated.
With Ebola, the spike protein may be the only accessible target, Ollmann Saphire said.
But in the later stages the sequence of units in the gene stabilized, as if the spike protein was then just right for attacking human cells.
The virus particle has surface spikes proteins that are club-shaped and are evenly dispersed over the surface.
During the viral replication cycle, spikes proteins mature in the host cell Golgi complex with a high mannose glycosylation.
Other terms for such a protein are M protein, M component, spike protein, or paraprotein.
The Chinese researchers gave special attention to one of the SARS virus's tools for entering a cell, known as the spike protein.
They lack both the external scaffolding protein D and the major spike protein G of the species in the genus Microvirus.
A research team at the Clinical Research Institute of Montreal is helping unlock the secrets of spike proteins.
Two other SARS vaccines, a recombinant spike protein and a modified vaccinia virus are also close to being tested in animal trials.
But until that is known, Dr. Holmes said, it makes sense to study the SARS spike protein and to try to find its receptor.
In SARS-CoV the ectodomain of the spike protein is responsible for attachment to and entry into cells during infection.
Moesin (for membrane-organizing extension spike protein) is a member of the ERM protein family which includes ezrin and radixin.
The evolution of the spike protein from its animal to human attack mode began in mid-November and was complete by the end of February, a mere 15 weeks later.
Sc-BatCoV-512 shares a common evolutionary origin in the spike protein of Bat-SARS CoV.
Out of this research, the team identified a drug that interferes with the spike protein, impairing the virus's ability to reproduce within – and ultimately kill – a host cell.
The mature product of the env gene is the viral spike protein, which has two main parts: the surface protein (SU) and the transmembrane protein (TM).
