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All patients with ulcerative colitis were in clinical remission and had normal levels of haemoglobin, C-reactive protein, and serum orosomucoid.
Orosomucoid and antitrypsin migrate together but orosmucoid stains poorly so alpha 1 antitrypsin (AAT) constitutes most of the alpha-1 band.
Disease activity was indicated by the following: increased stool frequency, abdominal pain, weight loss, growth failure, raised erythrocyte sedimentation rate (ESR), raised serum orosomucoid, and reduced serum albumin concentration.