nuclear scaffold

Thus, the nuclear scaffold places limits on what genes can and can not be expressed within a given cell and, hence, may serve a basis for cell identity.

It has been proposed that Drosophila chromosomes are attached to a nuclear scaffold at precise locations [ 13], but there is very limited mapping data on the position of these attachments.

It has been suggested that lamins provide a scaffold, essential for the assembly of the elongation complexes, or that it provides an initiation point for the assembly of this nuclear scaffold.

The nuclear scaffold is predicted to be relatively permanent for a given cell type, but induction of a signaling pathway-by ligand binding, cell:cell contact, or some other mechanism-can temporarily shift the expression profile.