nitrogen mustard

HN3 was the last of the nitrogen mustard agents developed.

In cancer chemotherapy, the first effective drug was nitrogen mustard.

As with Avastin, nothing about nitrogen mustard is changing but the price.

This chemical is a form of nitrogen mustard gas and a powerful vesicant.

They converted the base nitrogen mustard into a nontoxic "transport form".

These concerns led to the discovery of nitrogen mustard, a chemical warfare agent, as an effective treatment for cancer.

It is a nitrogen mustard alkylating agent and can be given orally.

Nitrogen mustard was initially tested as a chemical weapon.

Chemically it is a derivative of nitrogen mustard and uracil.

Steroids or nitrogen mustard applied to the skin.

Mechlorethamine belongs to the group of nitrogen mustard alkylating agents.

The nitrogen mustards are cytotoxic chemotherapy agents similar to mustard gas.

Nitrogen mustards that can be used for chemical warfare purposes are tightly regulated.

The original nitrogen mustard drug, mustine (HN2), is no longer commonly in use.

Due to its use in previous studies, the nitrogen mustard known as "HN2" became the first chemotherapy drug mustine.

In 1942, researchers at Yale University tested one such agent, nitrogen mustard, in a human for the first time.

This chemist was unable however to produce the nitrogen mustard or binary mustard as the group had wanted.

The most obvious was to seek better compounds than the original nitrogen mustards, and numerous alkylating agents emerged during the following 30 years.

They exchanged a nitrogen molecule for sulfur and had a more stable compound in nitrogen mustard.

This incident, combined with studies done on nitrogen mustard during the war, led to the post war development of the first chemotherapy drug Mustine.

Often abbreviated HN1, it is a powerful vesicant and a nitrogen mustard gas used for chemical warfare.

Nitrogen mustards react via an initial cyclization to the corresponding aziridinium salt.

It was designed as a military agent and is the only one of the nitrogen mustards that is still used for military purposes.

An overview of the sulfur and nitrogen mustard agents (Caution: contains graphic images)

It was a hazardous undertaking: everyone thought of the nitrogen mustards as dangerous compounds which could destroy vital cells in many organs.