microvillous atrophy
microvillous inclusion disease , MVID (Abkürzung)

Congenital lack of microvilli in the intestinal tract causes microvillous atrophy, a rare, usually fatal condition found in new-born babies.

Microvillous inclusion disease was first described in 1978 by Davidson et al.

Microvillous inclusion disease is thought to be extremely rare; only approximately 200 cases have been identified in children in Europe.

Mutations of MYO5B causes microvillous inclusion disease.

On 26 June 2009 a six year old girl diagnosed with microvillous inclusion disease became the third person in the UK to die of swine flu.

The appearance of microvillous inclusion disease on light microscopy is similar to celiac sprue; however, it usually lacks the intraepithelial lymphocytic infiltration characteristic of celiac sprue and stains positive for carcinoembryonic antigen (CEA).