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The work provided the foundation for the vaginal use of gels containing organic mercurial compounds as aids to contraception.
Early in the twentieth century, when the success of Ehrlich's organic compounds had been recognized, organic mercurial compounds were tested as treatments for syphilis.
Organic mercurial compounds, such as methylmercury, have a high affinity for sulfhydryl groups, which causes dysfunction of the enzyme choline acetyltransferase.
Before the characterization of TEA, mercurial compounds were among the only known blockers of AQP1, affecting both the constitutive water flux and the regulated ion conductance [ 6 10 ] .
A. Vogl wrote a charming account of how, as a young doctor on the wards of a Vienna hospital, he discovered that patients passed very large volumes of urine after they had received injections of one of the new organic mercurial compounds.
