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A mature teratoma often contains several different types of tissue such as skin, muscle, and bone.
A mature teratoma is a grade 0 teratoma.
Unlike a mature teratoma, it contains primitive neuroepithelium.
Data suggest that relapse rates are higher in patients with histologic evidence of lymphatic or venous invasion and lower when the primary tumor contains mature teratoma.
Cysts within mature teratoma may have partially developed organ systems; reports include cases of partial cranial bones, long bones and a rudimentary beating heart.
Extraspinal ependymoma, usually considered to be a glioma (a type of non-germ cell tumor), may be an unusual form of mature teratoma.
A struma ovarii (literally: goitre of the ovary) is a rare form of mature teratoma that contains mostly thyroid tissue.
Fetus in fetu and fetiform teratoma are rare forms of mature teratoma that include one or more components resembling a malformed fetus.
In this regard, it is noteworthy that in many cases the fetus in fetu is reported to occupy a fluid-filled cyst within a mature teratoma.
Fetus in fetu may be a very highly differentiated form of dermoid cyst, itself a highly differentiated form of mature teratoma.
Recurrence with malignant endodermal sinus tumor has been reported in cases of formerly benign mature teratoma, even in fetiform teratoma and fetus in fetu.
A mature teratoma is typically benign and found more commonly in women, while an immature teratoma is typically malignant and is more often found in men.