maturation arrest

Bone marrow shows erythroid hyperplasia with a maturation arrest.

The maturation arrests resulted in a fall in autoantibody production, thought to be a crucial component of lupus causation.

The adjacent testicular tissue commonly shows intratubular germ cell neoplasia, and may also show variable spermatocytic maturation arrest.

Testicular failure includes absence of failure production as well as low production and maturation arrest during the process of spermatogenesis.

Bone marrow is typically hypocellular, with maturation arrest in the myeloid lineages that give rise to neutrophils, macrophages, platelets and red blood cells.

It is currently unclear as to whether cancer stem cells arise from adult stem cell transformation, a maturation arrest of progenitor cells, or as a result of dedifferentiation of mature cells.

Aplastic crisis with dramatic fall in hemoglobin level and (reticulocyte count)-decompensation, usually due to maturation arrest and often associated with megaloblastic changes; may be precipitated by infection, such as influenza, notably with parvovirus B19.

Recognized patterns include: normal spermatogenesis, hypoplasia or hyposperm ato genesis, complete or early maturation arrest, Sertoli cell-only or germ cell aplasia, incomplete or late maturation arrest, and sclerosis.

The FNA patterns for hypospermatogenesis, Sertoli cell-only, early maturation arrest, and late maturation arrest show different ratios of these three cell types relative to normal spermatogenesis and are relatively easy to categorize in this way.