marker protein

In molecular biology, olfactory marker protein is a protein involved in signal transduction.

CD14 takes its name from its inclusion in the cluster of differentiation group of cell surface marker proteins.

Researchers developed a designer drug called Herceptin that interferes with the marker protein and helps to control advanced breast cancer.

Research on CBs was accelerated after discovery and cloning of the marker protein p80/Coilin.

For example, researchers have discovered that 30 percent of breast cancers produce unusually high amounts of a marker protein called HER-2/neu, which renders them particularly ferocious.

In 1990, researchers found a way to safely and reliably track termites using immunoglobulin G (IgG) marker proteins from rabbits or chickens.

Antibodies against PML and topoisomerase IIIα [ 33] were used as marker proteins for the NBs.

S100A9/A8 (synonyma: Calgranulin A/B; Calprotectin) are also regarded as marker proteins for a number of inflammatory diseases in humans, especially in rheumatoid arthritis.

Researchers hope that by vaccinating a patient with telltale pieces of a cancer cell, they can spur the immune system to mount a fierce response against all cells in the body that bear those distinguishing marker proteins.

Now, instead of a bone puncture, the donor is injected with a cytokine that makes the stem cells proliferate and enter the bloodstream, where they can be captured by virtue of characteristic marker proteins they carry on their surface.

DLGAP2 has been shown to interact with DLG4, the canonical synapse marker protein, which in turn binds to N-methyld-aspartate (NMDA) receptors and Shaker-type K+ channels.

Co-transfection and parallel transfection experiments using a non-secreted marker protein (β -galactosidase plasmid) confirmed that GGF activity in conditioned medium results from secretion and not simply from cell lysis or leakage.

The ovarian cancer patient experienced a 50% decline in the amount of the ovarian cancer marker protein CA-125 in her blood as well as a significant decrease in the number of cancerous cells in her ascitic fluid.

Evidence that these MSCs are pluripotent, rather than being a mixture of committed progenitor cells each with a restricted potential, includes their rapid proliferation in culture, a characteristic morphology, the presence of typical marker proteins, and their consistent differentiation into various mesenchymal lineages.

In analogy to eukaryotic cytokines, they interfere with host cell functions and change the morphology of monocytes, inducing the expression of the surface marker protein CD11b, phagocytic activity, as well as cell adherence, which are indicative of monocyte differentiation into macrophages.

PrP is the marker protein used in diagnostics for transmissible spongiform encephalopathies (TSEs), examples of which include bovine spongiform encephalopathy in cattle (i.e. "mad cow" disease), scrapie in sheep, and Creutzfeld-Jakob disease in humans.