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Children with pseudo-hermaphroditism and/or renal disease (glomerulonephritis or nephrotic syndrome) who develop Wilms tumor may have the Denys-Drash or Frasier syndrome (characterized by male hermaphroditism, primary amenorrhea, chronic renal failure, and other abnormalities),[20] both of which are associated with mutations in the WT1 gene.
Medizinwörterbuch für Ạ̈rzte und Krankenschwestern