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An analogous region in the lower limbs occurs at the lumbar enlargement.
In rats specifically this maturation occurs during the perinatal period when brain stem projects reach the lumbar enlargement.
The lumbar enlargement (or lumbosacral enlargement) gives attachment to the nerves which supply the lower limbs.
The lumbar enlargement, located between L1 and S3 spinal segments, handles sensory input and motor output coming from and going to the legs.
This is true of the α-MNs innervating the upper and lower limbs: these α-MNs form large cell columns that contribute to the cervical and lumbar enlargements of the spinal cord.
The Bastian-Bruns sign, or Bastian-Bruns law, is the loss of tone and deep tendon reflexes in the lower limbs in the presence of complete transection of the spinal cord above the level of the lumbar enlargement.
Throughout the cervical and thoracic regions the central canal is situated in the anterior third of the medulla spinalis; in the lumbar enlargement it is near the middle, and in the conus medullaris it approaches the posterior surface.