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Based on structural and functional similarities, membrane receptors are mainly divided into 3 classes: The ion channel-linked receptor; The enzyme-linked receptor and G protein-coupled receptor.
For example, group I mGluRs are known to increase the activity of N-methyl-D-aspartate receptors (NMDARs), a type of ion channel-linked receptor that is central in a neurotoxic process called excitotoxicity.
Wörterbuch für Biologie