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Treatment with anti-estrogens can modulate the secretion of insulin-like growth factor binding proteins.
This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs).
There are exceptionally low levels of insulin-like growth factor (IGF-1) and its principal carrier protein, insulin-like growth factor binding protein 3.
Insulin-like growth factor binding protein, acid labile subunit, also known as IGFALS, is a protein which in humans is encoded by the IGFALS gene.
Chen C, Lewis SK, Voigt L, et al.: Prostate carcinoma incidence in relation to prediagnostic circulating levels of insulin-like growth factor I, insulin-like growth factor binding protein 3, and insulin.