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They should also not be removed if the infant has hypoprothrombinemia.
Various rare diseases involving prothrombin have been described (e.g., hypoprothrombinemia).
A blood disorder such as hemophilia or hypoprothrombinemia: Aspen contains a chemical that is very similar to aspirin.
Several cephalosporins are associated with hypoprothrombinemia and a disulfiram-like reaction with ethanol.
Hypoprothrombinemia can be treated with periodic infusions of purified prothrombin complexes.
Hypoprothrombinemia."
Borchegrevink CF, et al. xStudy of congenital hypoprothrombinemia.
Hypoprothrombinemia can be the result of a genetic defect, may be acquired as the result of another disease process, or may be an adverse effect of medication.
Van Steenbergen W, Vermylen J. Reversible hypoprothrombinemia in a patient with primary biliary cirrhosis treated with rifampicin.
For example, 5-10% of patients with systemic lupus erythematosus exhibit acquired hypoprothrombinemia due to the presence of autoantibodies which bind to prothrombin and remove it from the bloodstream (lupus anticoagulant-hypoprothrombinaemia syndrome).
Select a reason CHD Cholesterol Coronary heart disease Cystic fibrosis Heart disease Hemorrhagic disease High cholesterol Hypercholesterolemia Hyperlipidemia Hypoprothrombinemia Low bone density Osteoporosis Warfarin anticoagulation Warfarin overdose Other General Health & Wellness (required)
As the antibiotic is broken down in the body, it releases free NMTT, which can cause hypoprothrombinemia (likely due to inhibition of the enzyme vitamin K epoxide reductase) and a reaction with ethanol similar to that produced by disulfiram (Antabuse), due to inhibition of aldehyde dehydrogenase.