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All were created to deal with looming losses to generic competitors.
Individual companies make more direct attacks on generic competitors.
The company said pharmaceuticals were hurt by the intrusion of generic competitors.
Nonetheless, some elegant advances distinguish it from the generic competitors.
In 2001, the company fought to fend off generic competitors to Glucophage.
But Pfizer badly needs to get new medicines to market to replace sales it is losing to generic competitors.
Dolobid lost its American patent protection in 1989 but has not yet faced a generic competitor.
Most savings in oncology drug reimbursements would involve drugs that have cheaper, generic competitors.
That has enabled clotrimazole to capture a significant share of the market before other generic competitors enter.
The bill would also tighten a loophole that allows brand-name companies to pay generic competitors not to bring their drugs to market promptly.
If a generic company succeeded in having a patent invalidated, it could then immediately market the drug, with no generic competitors, for 180 days.
In all its bilateral agreements, the United States is using its economic muscle to help big drug companies protect their products from generic competitors.
The Food and Drug Administration has yet to approve generic competitors for these drugs, but analysts expect ones to appear in the future.
One provision would allow only one automatic 30-month stay at most in patent infringement litigation against a generic competitor.
Claritin will soon face generic competitors.
Scott Henry, an analyst at Oppenheimer, said that companies must market new drugs heavily to prevent prescriptions from going to much cheaper generic competitors.
Although most of Medicare's savings on cancer drugs would involve treatments with generic competitors, prices for drugs without such competition would also be reduced.
As it loses sales to generic competitors, Pfizer must show that it can find new drugs like SU-11248, he said.
For years, firms have made their ways into the global market by researching generic competitors to patented drugs and following up with litigation to challenge the patent.
But instead of having the period all to itself - and thus being able to keep all the profits - it finds itself facing a generic competitor.
The Warner-Lambert Company, which has already felt the sting from generic competitors, said yesterday that profits fell 11 percent, to $123 million, in the quarter.
Otherwise, the commission may find itself powerless to block one of the more underhanded tactics used by brand-name drug manufacturers to keep generic competitors off the market.
Rather than risk it all, a brand-name manufacturer may choose to pay its generic competitor substantial compensation to drop its challenge and delay marketing its drug.
Pfizer Inc., which has a strong lineup of recently introduced drugs not threatened by generic competitors, reported 24 percent increases last week in both sales and net income.
Dr. Dong's study compared the effectiveness of Boots' thyroid drug, Synthroid, with a generic competitor.