estramustine

There may be other drugs that can interact with estramustine.

Your doctor or pharmacist can provide more information about estramustine.

Take estramustine on an empty stomach, at least 1 hour before or 2 hours after a meal.

If a man fathers a child while taking estramustine, the baby may have birth defects.

Ask your doctor how long you should continue using condoms after you stop taking estramustine.

Estramustine may also be used for other purposes not listed in this medication guide.

Tell any doctor who treats you that you are using estramustine.

Estramustine is used to treat metastatic or progressive prostate cancer.

It has been derivatized into the estrogen analogue estramustine, used to treat prostate cancer.

Calcium can make it harder for your body to absorb estramustine, which could make it less effective.

Estramustine can be prepared directly from estradiol.

If you have any of these other conditions, you may need a dose adjustment or special tests to safely take estramustine:

You should not use this medication if you are allergic to estramustine, or if you have:

Estramustine is indicated for the palliative treatment of metastatic and/or progressive carcinoma of the prostate.

Estramustine is a cancer medication that interferes with the growth of cancer cells and slows their growth and spread in the body.

Estramustine is marketed in the United States by Pharmacia (now a subsidiary of Pfizer)

Calcium can interfere with the absorption of other drugs (e.g., levothyroxine, quinolone antibiotics such as ciprofloxacin, tetracycline antibiotics, iron, estramustine).

Docetaxel Mitoxantrone Estramustine Paclitaxel Etoposide Chemotherapy may be helpful when prostate cancer no longer responds to hormone therapy.

Petrylak DP, Macarthur RB, O'Connor J, et al.: Phase I trial of docetaxel with estramustine in androgen-independent prostate cancer.

Before taking estramustine, tell your doctor if you have a history of stroke or heart attack, diabetes, heart disease, high blood pressure, migraine headaches, seizures, liver or kidney disease, or Paget's disease.

Hudes GR, Greenberg R, Krigel RL, et al.: Phase II study of estramustine and vinblastine, two microtubule inhibitors, in hormone-refractory prostate cancer.

Petrylak DP, Tangen CM, Hussain MH, et al.: Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer.

Pienta KJ, Redman B, Hussain M, et al.: Phase II evaluation of oral estramustine and oral etoposide in hormone-refractory adenocarcinoma of the prostate.

You should not use this medication if you are allergic to estramustine, or if you have a blood clot, swelling of a vein caused by a blood clot, or if you have ever had an allergic reaction to estradiol or nitrogen mustard.