cytostasis

Cytostasis is an important prerequisite for structured multicellular organisms.

However, other studies show there could be other targets that are responsible for producing long-lasting cytostasis in cells.

Nitric oxide induced cytostasis targets ribonucleotide reductase by rapid and reversible inhibition.

It was concluded that LAP can deliver at least one of the triggering signals necessary for inducing macrophage activity that leads to cytostasis.

Nitric Oxide - activated macrophages produce large amounts of nitric oxide(NO) which induces both cytostasis and cytotoxicity to tumor cells both in vitro and in vivo.

Active compounds are selected for testing based on several criteria: disease type specificity in the in vitro assay, unique structure, potency, and demonstration of a unique pattern of cellular cytotoxicity or cytostasis, indicating a unique mechanism of action or intracellular target.