cytoplasmic inclusion

Electron microscopy of cardiac biopsies show pathognomonic cytoplasmic inclusion bodies.

This protein accumulation forms proteinaceous cytoplasmic inclusions called Lewy bodies.

A definitive diagnosis can only be made pathologically on finding abundant glial cytoplasmic inclusions in the central nervous system.

Recent studies have shown that the major filamentous component of glial and neuronal cytoplasmic inclusions is alpha-synuclein.

Cytoplasmic inclusions are pinwheels.

Currently, a confirmed diagnosis of MSA can only be made post-mortem as glial cytoplasmic inclusion bodies are visible.

Cytoplasm - a gelatinous, semi-transparent fluid that fills most cells, it includes all cytosol, organelles and cytoplasmic inclusions.

"Halberstädter-Prowazek bodies": Cytoplasmic inclusion bodies located near the nuclei of conjunctival epithelial cells in trachoma.

Intracellular deposition of misfolded protein aggregates into ubiquitin-rich cytoplasmic inclusions is linked to the pathogenesis of many diseases.

Microscopically, poxviruses produce characteristic cytoplasmic inclusions, the most important of which are known as Guarnieri bodies, and are the sites of viral replication.

WMV also has different cytoplasmic inclusion bodies that can differentiate it from PRSV-W.

The hypertrophied cells are frequently perivascular in distribution and are greatly enlarged due to large granular to foamy basophilic cytoplasmic inclusion bodies.

Spironolactone bodies are eosinophilic, round, concentrically laminated cytoplasmic inclusions surrounded by clear halos in preparations stained with hematoxylin and eosin.

Unique cytoplasmic inclusion bodies are aggregates of nonmuscle myosin heavy chain IIA, and are only present in granulocytes.

Why these aggregates form despite the existence of cellular machinery to recognize and degrade misfolded protein and how they are delivered to cytoplasmic inclusions are not known.

NSP2 is an RNA-binding protein that accumulates in cytoplasmic inclusions (viroplasms) and is required for genome replication.

Cytomegalovirus (CMV) is a DNA virus in the family Herpesviridae known for producing large cells with nuclear and cytoplasmic inclusions.

FTLD-TDP43 Type3 presents with many small neurites and neuronal cytoplasmic inclusions in the upper (superficial) cortical layers.

Histology showed severe panproctocolitis and ileitis (Fig 2A and 2B) with scanty intranuclear and cytoplasmic inclusion bodies suggestive of cytomegalovirus infection.

These are a subset of protoplasmic astrocytes that contain numerous cytoplasmic inclusions, or granules, that stain positively with Gömöri's chrome-alum hematoxylin stain.

The cytoplasmic inclusions containing mycRab24(D123I) were similar to those observed inside the nucleus, except that they were larger, with a diameter 2-3 times that of the nuclear particles (Fig.

FTLD-FUS; which is characterised by FUS positive cytoplasmic inclusions, intra nuclear inclusions, and neuritic threads.

A classical Lewy body is an eosinophilic cytoplasmic inclusion consisting of a dense core surrounded by a halo of 10-nm-wide radiating fibrils, the primary structural component of which is alpha-synuclein.

Histologically, the most distinctive features of rhabdoid tumors of the kidney (RTK) are rather large cells with large vesicular nuclei, a prominent single nucleolus, and in some cells, the presence of globular eosinophilic cytoplasmic inclusions.

The acute phase is characterized histologically by multifocal areas of nuclear pyknosis/karyorrhexis and numerous cytoplasmic inclusion bodies in the cuticular epithelium and the subcutis of the general body surface, all appendages, gills, hindgut, esophagus and stomach.