cord factor

Alternatively, cord factor was suspended at a concentration of 0.2 or 2 mg/ml in hexane.

This growth pattern is due to cord factor, a glycolipid, and contributes to the virulence of the organism.

Majority of strains possess the cord factor (trehalose 6-6' dimycolate) an important virulence factor.

Cord factor refers to trehalose dimycolate, a virulence factor and glycolipid cell-wall component of virulent strains of Mycobacterium tuberculosis and closely related species.

Cord factor was suspended at a concentration of 1 mg/ml in isopropanol and sonicated in a bath sonicator (model 3510; Branson Ultrasonic Corporation) for 5 min.

This system also contains refined mycobacterial products (cord factor, cell wall skeleton) as immunostimulants and bacterial monophosphoryl lipid A. Three different species oriented formulations of the adjuvant system are available.

Cording (mycobacterium) Technical Note In vitro stimulation of macrophages Purified cord factor was used to stimulate either mouse RAW 264.7 cells or bone marrow-derived macrophages.

LIT: Interferon-gamma independent formation of pulmonary granuloma in mice by injections with trehalose dimycolate (cord factor), lipoarabinomannan and phosphatidylinositol mannosides isolated from Mycobacterium tuberculosis: H. Takimoto, et al.; Clin.

Nocardial virulence factors are the enzymes catalase and superoxide dismutase (which inactivate reactive oxygen species that would otherwise prove toxic to the bacteria), as well as a "cord factor" (which interferes with phagocytosis by macrophages by preventing the fusion of the phagosome with the lysosome).