chemical mediator

After the chemical mediators of the acute response subside, late phase responses can often occur.

This suggests that the mechanism through which physical activity improves memory may in fact be through these chemical mediators.

The chemical mediators that provoke the muscle spasm appear to arise from mast cells.

Conversely, these hyperplastic features could be taken to imply epithelial remodelling possibly under the influence of a chemical mediator.

TNFα is a chemical mediator in the body, and it may enhance the wasting process in cancer patients as well.

The activating stimulus may include bacterial lipopolysaccharides, muramyl dipeptide, and other chemical mediators.

They secrete chemical mediators that are involved in defending against parasites and play a role in allergic reactions, such as asthma.

When an allergen like ragweed comes along, this cell bursts and gives off these chemical mediators like histamine, which cause the symptom.

Hormones are substances (chemical mediators) released from endocrine tissue into the bloodstream where they travel to target tissue and generate a response.

Recruiting immune cells to sites of infection, through the production of chemical factors, including specialized chemical mediators, called cytokines.

This kind of transport is mediated by VEGF, one of the chemical mediators of inflammation.

Szczeklik's main research interest include: cardiopulmonary diseases, aspirin-induced asthma, chemical mediators in diseases of circulatory and respiratory systems with special reference to eicosanoids.

The mechanisms include the activity of chemical mediators from damaged tissue such as leukotrienes, bradykinin, histamine, and metabolites of arachidonic and sympathetic activity.

Although TNF appears to be the dominant, other cytokines (chemical mediators) are likely to be involved in inflammation in RA.

Another mechanism that is thought to have a significant influence on delayed effects involves formed blood cells and chemical mediators, which cause brain lipid peroxidation (degradation of unsaturated fatty acids).

This tear in the disc ring may result in the release of inflammatory chemical mediators which may directly cause severe pain, even in the absence of nerve root compression.

In tumour-induced hypercalcaemia (TIH), chemical mediators produced by cancer cells increase bone resorption and impair calciuim excretion by directly affecting renal tubular excretion of calcium.

An H antagonist is a histamine antagonist of the H receptor that serves to reduce or eliminate effects mediated by histamine, an endogenous chemical mediator released during allergic reactions.

Watanabe J, Shinmoto H, Tsushida T. Coumarin and flavone derivatives from estragon and thyme as inhibitors of chemical mediator release from RBL-2H3 Cells.

Macrophages are responsible for the production of various cytokines, RNS and ROS, growth factors and chemokines as a response to activation signal such as chemical mediators, cytokines and lipopolysaccharide.

Once the mast cell-antibody-antigen complex is formed, a complex series of events occurs that eventually leads to cell degranulation and the release of histamine (and other chemical mediators) from the mast cell or basophil.

Once a T cell has recognized its particular antigen on the surface of an aberrant cell, the T cell becomes an activated effector cell, producing chemical mediators known as lymphokines that stimulate macrophages into a more aggressive form.

The staining is concentrated in small granules within the cellular cytoplasm, which contain many chemical mediators, such as histamines and proteins such as eosinophil peroxidase, ribonuclease (RNase), deoxyribonucleases, lipase, plasminogen, and major basic protein.

Activated mast cells and basophils undergo a process called degranulation, during which they release histamine and other inflammatory chemical mediators (cytokines, interleukins, leukotrienes, and prostaglandins) from their granules into the surrounding tissue causing several systemic effects, such as vasodilation, mucous secretion, nerve stimulation, and smooth muscle contraction.

This feature is critical to omalizumab's pharmacological effects because a typical anti-IgE antibody can cross-link cell surface FcεRI-bound IgE, thereby aggregate FcεRI, and activate mast cells and basophils to discharge the horde of chemical mediators stored in the densely packed sacs inside the cells.