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The only other place that cardiolipin can be found is in the membranes of most bacteria.
The name 'cardiolipin' is derived from the fact that it was first found in animal hearts.
It is involved in the metabolism of cardiolipin.
It can also work to restore cardiolipin levels in the inner mitochondrial membrane.
One of its functions is to bind cardiolipin.
Cardiolipin from a cow heart is used as an antigen in the Wassermann test for syphilis.
In addition, the inner membrane is rich in an unusual phospholipid, cardiolipin.
As previously noted, contact sites are purported to have a unique lipid environment that is rich in cardiolipin.
Cardiolipin contains four fatty acids rather than two, and may help to make the inner membrane impermeable.
As there are four distinct alkyl chains in cardiolipin, the potential for complexity of this molecule species is enormous.
Syphilitic infection leads to the production of nonspecific antibodies that react to cardiolipin.
Dimers are connected by a cardiolipin molecule.
When bound the structure of cardiolipin and Apo-H both undergo large changes in structure.
Two phosphatidylglycerols form cardiolipin, the constituent molecule of the mitochondrial inner membrane.
The active t-Bid fragment is shown to localize to mitochondria through a positive interaction with cardiolipin.
The cell membranes of bacteria are rich in acidic phospholipids, such as phosphatidylglycerol and cardiolipin.
This distinction suggests that tBid might localize to contact sites because of the arrangement of cardiolipin there.
However, in most animal tissues, cardiolipin contains 18-carbon fatty alkyl chains with 2 unsaturated bonds on each of them.
It has a mutation in the gene coding for tafazzin, an enzyme involved in the biosynthesis of cardiolipin.
This can lower levels of hydroxyl radicals produced after an ischemia and prevent cardiolipin from being catabolized by phospholipase A2.
Additionally, it has been shown to bind to mitochondrial membrane lipid, cardiolipin and influence a change in the morphology of organelle.
Anti-cardiolipin antibodies are another type of AMA, cardiolipin is found on the inner mitochondrial membrane.
A sample of blood or cerebrospinal fluid is taken and introduced to the antigen - cardiolipin extracted from bovine muscle or heart.
Reactive oxygen species are known to cause the oxidation and loss of function of many lipids including cardiolipin [ 20 ] .
Phospholipase D (PLD) in the mitochondrion hydrolyses cardiolipin to phosphatidic acid.