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"Low carbohydrate diets improve atherogenic dyslipidemia even in the absence of weight loss."
A great deal has been written about LDL because it is thought to be atherogenic.
Reducing atherogenic risk in hyperlipemic humans with flaxseed supplementation: a preliminary report.
Cigarette smoking: The procoagulant and atherogenic effects of smoking increase the risk for silent stroke.
ApoE polymorphism and fish oil supplementation in subjects with an atherogenic lipoprotein phenotype.
This might reduce the length of exposure to the atherogenic factors of hyperglycaemia and disordered lipid metabolism.
Perlecan expression is down regulated by many atherogenic stimuli and thus Perlecan is thought to play a protective role in atherosclerosis.
In addition, hypothyroidism promotes atherogenic profile, and serum levels of total cholesterol and low-density lipoprotein (LDL) are increased.
The characteristics of the metabolic syndrome include atherogenic dyslipidemia, a prothrombotic state, insulin resistance, hypertension, and abdominal obesity [ 3 4 ] .
This reflects badly on those involved with diabetic care because it suggests that not enough attention has been devoted to discouraging this atherogenic activity in an atheroma-prone group.
Lovaza, through the stimulation of Lipoprotein Lipase, seems to stimulate the production of less atherogenic LDL species.
The USDA, in its food pyramid, promotes a low-fat diet, based largely on its view that fat in the diet is atherogenic.
In addition, Lp(a) transports the more atherogenic proinflammatory oxidized phospholipids which attract inflammatory cells to vessel walls, and leads to smooth muscle cell proliferation.
Thus, by the time of diagnosis of diabetes in middle age, these subjects may have already had 30 years or more of exposure to these atherogenic factors (Jarrett, 1984).
In addition, the emerging information regarding the properties of the platelet-derived growth factor argues for an important role in the atherogenic process of this platelet α-granule constituent.
Because plant sterol levels actually reflect cholesterol absorption, some have concluded elevated cholesterol absorption, not plant sterols are atherogenic or otherwise associated with CVD risk.
Large amounts may increase low-density lipoproteins (LDL) (see below), up to 46%, although LDL changes from small to larger, buoyant, less atherogenic particles.
In another study, rabbits fed atherogenic diets containing various oils were found to undergo the greatest amount of oxidative susceptibility of LDL via polyunsaturated oils.
The risk factors include abdominal obesity, meaning the excessive fat tissue in and around the abdomen, atherogenic dyslipidemia which is a blood fat disorder, and elevated blood pressure.
The mechanism and pathophysiological significance of this abnormality remain unclear, but it may be a remnant particle accumulation which might in itself be atherogenic (e.g., like LDL).
Hypertension and hypercholesterolaemia are common accompaniments of diabetes and it is not illogical to anticipate similar benefits if these atherogenic factors are dealt with effectively in the diabetic patient.
I theorized that even while still young and active, such athletes were laying down atherogenic plaques (calcification) in their coronary arteries and were asymptomatic while undergoing strenuous activities.
Each abnormality promotes atherosclerosis independently, but when clustered together, these metabolic disorders are increasingly atherogenic and enhance the risk of cardiovascular morbidity and mortality [ 1 ] .
Genistein, the dietary-derived angiogenesis inhibitor, prevents LDL oxidation and protects endothelial cells from damage by atherogenic LDL.
Although the increase in LDL-C may be more focused on the larger LDL particles, which may be less atherogenic, the clinical significance of this is currently unknown.