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G protein spikes out of the membrane and acts as a major antigenic determinant.
The viral neuraminidases are frequently used as an antigenic determinants found on the surface of the Influenza virus.
In this early paper he demonstrated that the antibody molecule has two combining sites with the same specificity for an antigenic determinant.
Research will identify antigenic determinants important for host protection and hopefully engineer their increased expression in the vaccine, thereby improving its efficacy still further.
An idiotope is the unique set of antigenic determinants (epitopes) of the variable portion of an antibody.
The antigenic determinant for the blood group Ss is located at residue 29 where S has a methionine and s a threonine.
The antigenic determinants of serum IgG and IgA responses are shown in Figure 3.
Hence identification of antigenic determinants of IgA response may lead us towards antibody responses likely to be important in parasite clearance.
Affinity is a measure of the binding strength between epitope (antigenic determinant) and paratope (antigen-binding site of an antibody).
He defined idiotype as the set of epitopes on the V region of an antibody molecule, where epitope means an antigenic determinant.
Precipitation occurs with most antigens because the antigen is multivalent (i.e. has several antigenic determinants per molecule to which antibodies can bind).
Epitope - The distinct molecular surface features of an antigen capable of being bound by an antibody (a.k.a. antigenic determinant).
Autoantibodies targeted at different antigenic determinants on red cells and platelets are assumed to cause isolated episodes of hemolytic anemia and thrombocytopenia, respectively.
In molecular biology, the protein domain VEK-30, is a 30-amino acid long, internal peptide present within bacterial organisms that acts as an epitope or antigenic determinant.
An epitope, also known as antigenic determinant, is the part of an antigen that is recognized by the immune system, specifically by antibodies, B cells, or T cells.
Cohen-Kashi KJ, Lukacher A. Identification of Antigenic Determinants for Polyoma virus - Specific T-cell Hybridomas.
A potential explanation for this may relate to the demonstration that citrulline appears to be an essential constituent of the antigenic determinants recognized by AKA, APF, and AFA.
The antigenic determinants of the serum IgM, IgG, and IgA responses in patients were determiend by SDS-PAGE and immunoblotting.
Immunohistochemical studies using monoclonal antibodies have added further information as there is a peculiar pattern of expression of surface antigenic determinants which is not seen in normal colon, infectious colitis, or graft- versus -host disease.
Glycophorins A (GYPA; this protein) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups.
Together, these data are most consistent with the hypothesis that individual RA patients respond to unique antigenic determinants, that may preferentially be citrullinated, but that are likely distinct from those of targeted by other RA patients.
Analysis of the antigenic determinants of the IgG and IgA responses by immunoblotting showed that patients with chronic infection unlike those who clear the infection have no IgA response to a 57 kDa Giardia heat shock antigen.
In 1990 and 1995, he and his colleagues at Affymax applied for the patents of antigenic determinants obtained using a pathogenic agent or a derivative that presents a restricted set of antigens, and recombinant DNA clone from Plasmodium falciparum.
The serological characters represented as the antigenic determinants of CPsV-EG isolate related to monoclonal antibodies specific CPsV strain where as appeared precipitation reaction by DAS-ELISA and DTBIA (Ghazal et al., 2008).
The sharing of antigenic determinants by germ free rat colon and a lipopolysaccharide extract of Escherichia coli suggests that the anticolon antibodies and associated cell mediated cytotoxicity may result from stimulation of the gut associated lymphoid tissue by cross reacting enterobacterial antigens.