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A man in the audience shouted, "I remember: alkalize with Alka Seltzer!"
Lithium hydroxide (isotopically enriched in lithium-7) is used to alkalize the reactor coolant in pressurized water reactors for corrosion control.
By itself, apical HCl secretion would progressively alkalinise the parietal cell and deplete it of Cl -.
Simultaneously, there is downregulation of the basolateral transport systems which act to alkalinise the cell: Na + -HCO 3 -co-transport and, possibly, Na + /H + exchange (although this has been disputed).