acute toxicity tests

Unfortunately, use of acute toxicity tests remains widespread in industry.

There are several different types of acute toxicity tests.

The results from acute toxicity tests can thus help determine whether the effect identified is due to a specific contaminant.

Acute toxicity tests are normally 24-96 hours, whereas chronic tests will typically run for a week or longer.

Lethality is most common effect used in toxicology and used as an endpoint for acute toxicity tests.

Data from acute toxicity tests performed as part of permit requirements are evaluated during compliance evaluation inspections and performance audit inspections.

Furthermore, they may be used in in vivo acute toxicity tests of dermal irritation and sensitization.

Current European legislation demands that "acute toxicity tests must be carried out in two or more mammalian species" covering "at least two different routes of administration".

These procedures, called whole effluent toxicity tests, include acute toxicity tests as well as chronic test methods.

While all of the acute toxicity tests suffer from serious scientific shortcomings, I am most familiar as an ophthalmologist with the notorious Draize eye irritation test.

Acute Effluent Toxicity Tests are used to monitor the quality of industrial effluent monthly using acute toxicity tests.

The test was also compared to acute toxicity tests using Atlantic silverside, Menidia menidia, and the mysid, Mysidopsis bahia, and five metals.

Comparison of these values derived from the model, have repeatedly been found to be comparable to the results of lethal tissue concentrations from acute toxicity tests (Arnold et al. 2005).

The majority of studies that measure toxicity of pesticides to Apis mellifera honeybees focus on estimating the lethal dose (LD50) in acute toxicity tests to adult honeybees.

Where applicable, foods used only in acute toxicity tests can be compared with a food of known quality in side-by-side, multi-concentration acute tests, using the reference toxicant regularly employed in the laboratory QA program.

With the exception of the Holmesimysis costata Acute Test (Table 19), the methods included in this manual are referenced in Table IA, 40 CFR Part 136 regulations and, therefore, constitute approved methods for acute toxicity tests.

In this study, the results from laboratory acute toxicity tests of TBT on periphyton corroborated the results from the field study, supporting the conclusion that toxicity to periphyton resulted from TBT pollution at the site under investigation.

INTRODUCTION 1.1 This manual describes acute toxicity tests for use in the National Pollutant Discharge Elimination System (NPDES) Permits Program to identify effluents and receiving waters containing toxic materials in acutely toxic concentrations.