aconitine

In China, aconitine is also used as a herbal medicine against pain.

I wondered who it was who knew I'd been reading the article on aconitine.

There was also an attempt to obtain aconitine, which was not Successful.

Aconitine is very toxic due to different reactive groups.

A lethal dose of aconitine is 3-4 mg.

Animal experiments have shown that the mortality of aconitine is lowered by tetrodotoxin.

Aconitine can interact with the voltage-dependent sodium-ion channels.

Aconitine belongs to the family of aconitum alkaloids and are barely soluble in water.

Also Paeoniflorin seems to have a detoxifying effect on the acute toxicity of aconitine in test animals.

They contained aconitine.'

Aconitine is a potent neurotoxin that opens tetrodotoxin-sensitive sodium channels.

Aconitine is a toxin produced by the Aconitum plant, also known as devil's helmet or monkshood.

Aconitine suppresses the conformational change in the sodium-ion channel from the active state to the inactive state.

Aconitine is also soluble in mixtures of alcohol and water, if the concentration of alcohol is high enough.

Aconitine binds to the receptor at the neurotoxin binding site 2 on the alpha-subunit of the channel protein.

The researchers used recombinants of these eight different CYPs and incubated it with aconitine.

The drug aconite (which contains several alkaloids, including aconitine, a highly poisonous substance) is extracted from the dried monkshood root.

Extracts from plants containing toxic alkaloids, such as aconitine and tubocurarine, were used since antiquity for poisoning arrows.

Christison had taught that aconitine was undetectable but forensic science had improved since Lamson's student days.

In medieval Europe, the toxic entheogen Aconitine was believed to prevent werewolves from undergoing their dire transformations.

The toxic effects of aconitine were attenuated by tetrodotoxin, probably due to their mutual antagonistic effect on excitable membranes.

Police found thallium in his pocket and antimony, thallium and aconitine in his flat.

Aconitine was the poison used by George Henry Lamson in 1881 to murder his brother-in-law in order to secure an inheritance.

In neurons, aconitine increases the permeability of the membrane for sodium-ions, resulting in a huge sodium-influx in the axon terminal.

The results indicate that aconitine was mainly metabolized by CYP3A4, 3A5 and 2D6.