Virchow-Robin space

In addition, a Virchow-Robin space has no mass effect and is located along the blood vessel around which it forms.

Virchow-Robin spaces may be enlarged to a diameter of five millimeters in healthy humans and are usually harmless.

Much of the current research concerning Virchow-Robin spaces relates to their known tendency to dilate.

Virchow-Robin spaces are lymphatic spaces between the vessels of the central nervous system.

The clinical significance of Virchow-Robin spaces comes primarily from their tendency to dilate.

Virchow-Robin spaces are distinguished on an MRI by several key features.

Virchow-Robin spaces are gaps containing interstitial fluid that span between blood vessels and the brain matter which they penetrate.

Like the blood vessels around which they form, Virchow-Robin spaces are found in both the subarachnoid space and the subpial space.

The appearance of Virchow-Robin spaces was first noted in 1843 by Durand Fardel.

Dilated Virchow-Robin spaces are categorized into three types:

Enlarged Virchow-Robin spaces have been observed most commonly in the basal ganglia, specifically on the lenticulostriate arteries.

The eponymous Virchow-Robin spaces are named after him and pathologist Rudolf Virchow.

The ideal method used to visualize Virchow-Robin spaces is T2-weighted MRI.

At one point in time, dilated Virchow-Robin spaces were so commonly noted in autopsies of persons with dementia, they were believed to cause the disease.

Virchow-Robin spaces ultimately drain fluid from neuronal cell bodies in the CNS to the cervical lymph nodes.

Virchow-Robin spaces (VRS) are perivascular, fluid-filled canals that surround perforating arteries and veins in the parenchyma of the brain.

Paranasal sinus or mastoid lesions were found in more than 50% versus 20% of controls, and accentuated Virchow-Robin spaces in 70% of patients versus 27% of controls.

The MR images of dilated Virchow-Robin spaces must be distinguished from MR images of other neurological maladies that are similar in appearance.

Type 3 dilated VRS are located in the midbrain Virchow-Robin spaces are most commonly located in the basal ganglia, thalamus, midbrain, cerebellum, hippocampus, insular cortex, the white matter of the cerebrum, and along the optic tract.

As an example, NM can develop from primary brain tumor or parenchymal metastasis when tumor cells are lodged in small central nervous system (CNS) vasculature causing local ischemia and vessel damage which result in tumor spillage into the Virchow-Robin spaces and providing access to the subarachnoid space.