V gene

Furthermore, superantigens react with all T cells carrying a particular V gene.

He demonstrated the importance of somatic hypermutation of immunoglobulin V genes in antibody affinity maturation.

Genetic variants in the Factor V gene is associated with an increased tendency to form blood clots, such as deep vein thrombosis (DVTs).

A controversial theory of Edward J. Steele's suggests that endogenous retroviruses carry new versions of V genes from soma cells in the immune system to the germ line cells.

Damle RN, Wasil T, Fais F, et al.: Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia.

This D-J recombination is followed by the joining of one V gene segment, from a region upstream of the newly formed DJ complex, forming a rearranged VDJ gene segment.