Semliki Forest virus

Some viruses, for example, the Semliki forest virus, enter the cell through this mechanism.

Semliki Forest virus is spread mainly by mosquito bites.

Middelburg virus, although classified as a separate complex, may be a member of the Semliki Forest virus group.

FeTMPS showed activity in this range also for parainfluenza-3, reovirus-1, and Semliki forest virus.

Barmah Forest virus is related to the Semliki Forest virus.

Semliki Forest virus has been used extensively in biological research as a model of the viral life cycle and of viral neuropathy.

Simons' group has also demonstrated that several other viruses, including influenza virus, also follow the entry path used by the Semliki Forest virus.

The Sindbis virus and Semliki Forest virus have been used to build recombinant alphavirus replicons.

Results require two to three days, and false positives can occur with infection via other related viruses, such as o'nyong'nyong virus and Semliki Forest virus.

The process begins when the Semliki Forest virus, which is enveloped in a membrane, enters the cell by endocytosis, leaving the virus surrounded by a double membrane (B4).

The Semliki Forest virus is a positive-stranded RNA virus with icosahedral capsid which is enveloped by a lipid bilayer, derived from the host cell.

The structure of the Semliki Forest virus revealed a structure that is similar to that of flaviviral glycoprotein E, with three structural domains in the same primary sequence arrangement.

The Semliki Forest virus was first isolated from mosquitoes in the Semliki Forest, Uganda by the Uganda Virus Research Institute in 1942.

The institute was the first to isolate more than 20 new arboviruses, including West Nile Virus, Bwamba Fever, Semliki Forest Virus, Orungo, Kadam, and O'nyong'nyong.

Una virus is a subtype of the Mayaro virus (MAYV), one of the Semliki Forest Virus (SFV) complex of the Togaviridae family.

Semliki Forest virus (SFV) and Sindbis virus (SIN) require cholesterol and sphingolipids in target membrane lipid rafts for envelope glycoprotein-mediated membrane fusion and entry.

Dr Kai Simons and his colleagues at the European Molecular Biology Laboratory recently undertook a detailed study of the entry of Semliki Forest virus (which can cause encephalitis in mice) into animal cells.

Alphaviruses are of interest to gene therapy researchers, in particular the Ross River virus, Sindbis virus, Semliki Forest virus, and Venezuelan equine encephalitis virus have all been used to develop viral vectors for gene delivery.

SDS represent a potentially effective topical microbicide, which can also inhibit and possibly prevent infection by various enveloped and non-enveloped viruses such as the Herpes simplex viruses, HIV, and the Semliki Forest Virus.

Hardy P.A., Mazzini M.J., Schweitzer C., Lundstrom K., Glode L.M. Recombinant Semliki forest virus infects and kills human prostate cancer cell lines and prostatic duct epithelial cells ex vivo.

The alphavirus-like superfamily includes more than 250 plant and animal viruses including Tobacco mosaic virus, Semliki forest virus, Hepatitis E virus, Sindbis virus, and arboviruses (which cause certain types of encephalitis) (Sullivan & Ahlquist, 1997; Lampio, 1999).

Sindbis virus, geographically restricted to the Old World, is more closely related to the eastern equine encephalitis subgroup, which are New World viruses, than it is to the Semliki Forest virus subgroup which is also found in the Old World.