Rathke's pouch

Rathke's pouch remains open to the outside, close to the nasal openings.

Rathke's pouch is an embryonic precursor of the anterior pituitary.

The cysts are the remainder of Rathke's pouch.

Rathke's pouch, and therefore the anterior pituitary, is derived from ectoderm.

The embryonic remnants of Rathke's pouch may undergo neoplastic change called a craniopharyngioma.

It develops from a depression in the dorsal wall of the pharynx (stomodial part) known as Rathke's pouch.

Rathke's pouch may develop benign cysts.

Note: The anterior pituitary develops from the ectodermal tissue of Rathke's pouch.

The anterior pituitary arises from an invagination of the oral ectoderm and forms Rathke's pouch.

He also first described in 1839 the embryonic structure, now known as Rathke's pouch, from which the anterior lobe of the pituitary gland develops.

In embryogenesis, Rathke's pouch is a depression in the roof of the developing mouth in front of the buccopharyngeal membrane.

Craniopharyngioma is a rare, usually suprasellar neoplasm, which may be cystic, that develops from nests of epithelium derived from Rathke's pouch.

The anterior wall of Rathke's pouch proliferates, filling most of the pouch to form pars distalis and pars tuberalis.

Ameloblastoma also occurs in long bones, and another variant is Craniopharyngioma (Rathke's pouch tumour, Pituitary Ameloblastoma.)

In some organisms, the proliferating anterior wall does not fully occupy Rathke's pouch, leaving a remnant (Rathke's cleft) between the pars distalis and pars intermedia.

Hemorrhage from a Rathke's cleft cyst, a remnant of Rathke's pouch that normally regresses after embryological development, may cause symptoms that are indistinguishable from pituitary apoplexy.

It is based upon the gross anatomical separation of the posterior and anterior pituitary along the cystic remnants of Rathke's pouch, causing the pars intermedia to remain attached to the neurohypophysis.

Together, these cellular signals stimulate a group of cells from the nasal cavity to form Rathke's pouch, which becomes independent of the nasal cavity and develops into the anterior pituitary; this process includes the suppression of production of a protein called Sonic hedgehog by the cells of Rathke's pouch.